TargTex to present Tumour Eradication in Rodents from its Nanoformed Glioblastoma drug

Press release

Nanoform Finland Plc

October 17, 2022

08:10 a.m. Finnish time / 07:10 a.m. Swedish time

TargTex to present Tumour Eradication in Rodents from its Nanoformed Glioblastoma drug

Helsinki, Finland – Nanoform, an innovative nanoparticle medicine enabling company, together with TargTex, a European biotech company, will present highly promising in-vivo data, enabled by nanoformed drug product for the treatment of Glioblastoma. This data was generated for a planned Phase1/2a clinical trial, due to commence in early 2024.

The presentation at 10:00am EDT on 25 October at PODD Conference (Partnerships and Opportunities in Drug Delivery) in Boston, USA, will be given by Dr João Seixas, CEO, TargTex and Christian Jones, CCO, Nanoform. At this time the presentation including the released data will also be made available on Nanoform’s website.

News of Nanoform’s PoC* success and subsequent GMP Agreement with TargTex was published in February 2022. Since then, the companies have further collaborated in the optimization of a hydrogel formulation for implantation at the site of the resected tumor. This process demands very small particles to increase drug loading and improve release profile. Other technologies and approaches previously failed to deliver the necessary performance.

“In a space where unfortunately no significant advances were seen in the latest two decades, this novel approach provides hope for patients, and I wish we had started this collaboration with Nanoform sooner.” Dr João Seixas, CEO, TargTex

“We are thrilled that Nanoform’s platform technologies are able to help this highly promising medicine reach the clinic.” Prof. Edward Hæggström CEO, Nanoform

*PoC refers to Nanoform’s Proof of Concept study to assess nanoforming feasibility for an API

For further information, please contact:

Christian Jones, CCO

[email protected] / +44 7804 474 771

For investor relations queries, please contact:

Henri von Haartman, Director of Investor Relations

[email protected] / +46 7686 650 11

About TargTex

TargTex (www.targtex.com), a European biotech company, is developing an innovative hydrogel based pharmaceutical product for a highly unmet medical need: Glioblastoma multiforme (GBM) treatment.  About 3 in 100,000 people develop the disease each year. GBM is the most aggressive type of cancer that begins within the brain and there is as of yet no efficacious treatment for this deadly disease. TargTex’s drug candidate has already shown efficacy in animal models.

About Nanoform

Nanoform is an innovative nanoparticle medicine enabling company. Nanoform works together with pharma and biotech partners globally to provide hope for patients in developing new and improved medicines utilizing Nanoform’s platform technologies. The company focuses on reducing clinical attrition and on enhancing drug molecules’ performance through its nanoforming technologies and formulation services. Nanoform’s capabilities include GMP manufacturing, and its services span the small to large molecule development space with a focus on solving key issues in drug solubility and bioavailability and on enabling novel drug delivery applications. Nanoform’s shares are listed on the Premier-segment of Nasdaq First North Growth Market in Helsinki (ticker: NANOFH) and Stockholm (ticker: NANOFS). Certified Adviser: Danske Bank A/S, Finland Branch, +358 40 744 1900. For more information, please visit www.nanoform.com.

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