Polymer Factory Sweden AB releases high mass calibrants for beta testing

According to the Company’s goals, Polymer Factory is working on an expansion of applications for its calibration technology SpheriCal® to increase the target group and with that the market potential of the platform. One of these application areas is high molecular weight calibration of high-performance MALDI-TOF suited for diagnostic applications including antibody research. The Company has now engaged selected partners for beta testing of its newly developed high molecular weight SpheriCal®, which were recently presented during the 71st ASMS Conference on Mass Spectrometry and Allied Topics (ASMS) earlier this summer.

CTO Michael Malkoch:

“Calibration in the high molecular weight range is very important to be able to accurately analyze larger molecules; both biomolecules, such as proteins or intact antibodies, to enable better or earlier diagnostics for viral or bacterial infections, and synthetic polymers for advanced synthetic material research. There are currently no high-performing synthetic calibrants commercially offered for these mass ranges, and Polymer Factory is aiming to take a good position in this growing market.”

During 2023, Polymer Factory has engaged collaborators for evaluations within other calibration areas, such as Electrospray Ionization Mass Spectrometry (ESI-MS) and Ion Mobility Spectrometry (IMS). The results of the IMS development were presented by Polymer Factory’s Product Manager at ASMS in June 2023, which got a lot of attention and will be published in the scientific literature soon.

About SpheriCal®

Polymer Factory has developed SpheriCal® calibration technology, designed for MS instruments that measures the mass of molecules. SpheriCal® is used as a high-performance calibrant to ensure the instruments do not provide misleading data. SpheriCal® is an innovative technology designed to meet the calibration requirements of matrix-assisted laser desorption ionization (MALDI) instruments. The MALDI-technique is applied to the analysis of biomolecules, e.g., DNA, proteins, peptides, and sugars, as well as large organic molecules including polymers, dendrimers, and other macromolecules, and for use in proteomics.