DexTech Medical AB Half-year report July 1 - December 31, 2024

Summary of the second quarter (2024-10-01 – 2024-12-31)

• Net sales amounted to MSEK 0,0 (0,0)
• Operating profit/loss amounted to MSEK -1,1 (-1,4)
• Earnings per share* SEK -0,05 (-0.06)

* Before and after dilution. Earnings per share: Profit for the period divided by the average number of shares 18,485,857. For the comparison period, the average number of shares was 18,485,857. Amounts in brackets refer to the corresponding period last year.

Summary of the first half-year (2024-07-01 – 2024-12-31)

• Net sales amounted to MSEK 0,0 (0,0)
• Operating profit/loss amounted to MSEK -2,4 (-2,5)
• Earnings per share* SEK -0.11 (-0.11)
• Cash and cash equivalents at the end of the period amounted to MSEK 16,3 (19,0)

* Before and after dilution. Earnings per share: Profit for the period divided by the average number of shares 18,485,857. For the comparison period, the average number of shares was 18,485,857. Amounts in brackets refer to the corresponding period last year.

Comments from the CEO 

Results from the Company's ongoing myeloma study show that three out of four patients had stable disease after completing treatment. Stable disease means a slowing down of the course of the disease where the cancer does not progress. The patients who can be included in the study (inclusion criteria), must have relapsed/treatment-resistant disease and received 1-5 prior lines of therapy. The results are very important and promising, indicating that OsteoDex can slow relapsed/treatment-resistant disease. In addition, a clear decreasing effect on biomarkers related to bone cells, especially osteoclasts activity (bone resorption) is noted. Significantly, no OsteoDex related serious adverse events (SAEs) have been noted. The study is progressing with the two higher dose ranges of 6mg/kg and 9mg/kg. Patients who achieve stable disease after completion of treatment will be followed up until new progression, according to the approved amendment, which provides information on how long the treatment effect lasts.

General information about the study: Conducted at Uddevalla Hospital, Dr Dorota Knut, and Dr Katarina Uttervall dept. Haematology/HERM, Karolinska University Hospital, Huddinge, Katarina Uttervall is principal investigator (PI).  Biomarkers are analysed at the Central Laboratory, Karolinska University Hospital, NKS, Solna. The primary objective is to confirm safety and tolerability and as a secondary objective to determine indications of treatment response. Documentation of quality of life will also be done (QoL scores). The maximum number of patients is reduced to 12 from the original 20. Primary and secondary objectives can be achieved despite lower patient numbers and are an adaptation to available patients that can be recruited.

The company's reduced costs will allow continued operations until Q4, 2026

Anders R Holmberg

Contact

Anders Holmberg, CEO, +46 73 324 27 82

Gösta Lundgren, CFO, +46 70 710 47 88

This information is such information that DexTech Medical AB is required to disclose in accordance with the EU Market Abuse Regulation. The information was submitted for publication on February 27, 2025 through the care of the above contact persons.

DexTech Medical AB is a Swedish research company that, based on its technology platform, has developed four drug candidates that are protected by patents. The lead candidate is OsteoDex for the treatment of castration-resistant prostate cancer (CRPC) with bone metastases. A successful clinical phase II study has been conducted with OsteoDex where the results show high tolerability with mild side effects and treatment effect on patients who fail existing drugs. DexTech's goal is to out-license each drug candidate no later than after completion of the phase II study. DexTech Medical AB is listed on the Spotlight Stock Market.